Episode 14
PNC-27: the Peptide That Targets the HDM2 Marker
PNC-27 is a 32-amino-acid research peptide built from two fused pieces and studied for its binding to the HDM2 surface marker. What cell-line research has measured, and what has not been shown.
Now playing · Episode 14
PNC-27: the Peptide That Targets the HDM2 Marker
Transcript
- Hi, Peppy here, and this is PNC27, a research peptide, 32
- amino acids long, built from two
- pieces fused together. One half comes from P53, a natural
- protein your body makes to keep cells in
- check. The other half is a guidance tag that finds a very
- specific surface marker called HDM2.
- Here's what makes it different. PNC27 is selective. It does
- not knock on every door.
- It only binds to cells with HDM2 on the outer membrane. How
- ? The guidance tag latches on.
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