Episode 5
Semax Peptide: the 7-Amino-Acid Fragment of ACTH
Semax is a seven-amino-acid peptide engineered from a fragment of ACTH. This explainer covers how it is being studied in cognition and attention research, and where the evidence runs out.

Now playing · Episode 5
Semax Peptide: the 7-Amino-Acid Fragment of ACTH
Transcript
- Hi, Peppy here, and this is CMAX, a 7-amino acid peptide
- engineered from a fragment of ACTH.
- While most peptides work on your body, CMAX works directly
- on your brain.
- Here's what it does.
- First, it boosts BDNF, the brain's own growth factor that
- helps neurons reach out,
- connect, and strengthen the pathways you use most.
- It also raises NGF, the protein that keeps your brain cells
- alive and active
- instead of letting them wither under stress.
- And it tunes your dopamine and glutamate signaling, the two
- systems behind focus, motivation,
- and the speed of your own thinking.
- Here's what people feel.
- Sharper focus, especially in the second half of a long
- working day.
- Less brain fog when you are tired or underslept.
- Faster mental processing on hard problems.
- More drive to actually start the thing in front of you.
- CMAX pairs naturally with Solanc, the calm to its sharpness
- .
- Many people use both together in a combination known as the
- Clarity Protocol.
- Add NAD Plus for cellular energy and you get the MIND
- protocol.