Episode 12
Kisspeptin-10: the 10-Amino-Acid Master Signal
Kisspeptin-10 is the shortest active piece of your body's own kisspeptin, the upstream signal for the reproductive hormone axis. What human and animal studies have measured about it.
Now playing · Episode 12
Kisspeptin-10: the 10-Amino-Acid Master Signal
Transcript
- Hi, Peppy here, and this is Kispeptin 10.
- It is a 10-amino acid peptide,
- the shortest active piece of your body's own Kispeptin.
- It is the master signal at the very top
- of your reproductive hormone axis.
- Here's what makes it different.
- Most hormone peptides act downstream.
- Kispeptin works at the source.
- It tells the brain to fire the signal
- that wakes up everything else.
- How?
- Kispeptin binds a receptor on a special group of neurons
- inside the hypothalamus.
- Those neurons release the upstream signal
- that travels to the pituitary.
- The pituitary then releases the hormones
- that drive the gonads.
- The entire chain restarts from the top.
- This means it does not push one hormone in isolation.
- It restores the rhythm of the whole axis.
- Here's what people feel.
- Morning drive returns and the body wakes up with energy.
- Libido and confidence build back
- in a way that feels natural and not forced.
- Mood steadies, the kind of steadiness
- that comes from healthy hormone levels.
- A sense that the engine has restarted from the inside.
- Many people pair it with ipamoralin pre-bed,
- the same upstream restart for the growth hormone axis.
- Together they cover the two axes that decline most with age
- .
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