Parkinson's Research: Dopamine, BDNF and Peptides | Peptide Research Explained

Now playing · Episode 49

Parkinson's Research: Dopamine, BDNF and Peptides

Transcript

Parkinson's. 10 million people live with it worldwide. Most
start by dismissing the early
signs. Here's what it feels like. You raise a cup of coffee
and watch your hand shake without
permission. You sign your name and the letters get smaller
as you go. You button your shirt and
your fingers do not move as smoothly as they used to. You
walk down the hallway and your feet stop
landing where you sent them. You turn to look behind you
and your whole body has to follow.
You look in the mirror and your face does not show what you
are feeling inside. Sleep gets shallow.
Mornings get heavy. Words come out softer than you remember
sending them. Here is what is happening
underneath. Deep in the brain, there is a small region that
acts like the volume knob for movement.
Inside it, a specific group of cells make dopamine, the
chemical that lets the brain send smooth signals
to the body. In Parkinson's, those cells slowly stop firing
. The volume knob gets turned down.
Movement signals reach the body weaker. The mitochondria
inside those cells run out of fuel.
And the cells that should protect the neurons get tired.
Two peptides can support this.
Semax is a small protective peptide built for the brain. It
crosses the blood-brain barrier
and tells the surviving cells to stay strong by boosting BD
NF, a growth factor that helps neurons
hold their connections. The cells most affected by
Parkinson's are exactly the ones Semax was designed
to support. NAD+ is the cofactor that powers every cell.
Levels drop with age and drop further when neurons are
under stress. Restoring it gives the surviving cells the
energy to keep firing. When the protective signal
is up and the cellular fuel is back, the system gets help
where it needs it most. The hand can feel steadier.
The morning can feel lighter. Sleep can come back. The face
can soften back into expression. Words can come out clearer
.
Not a cure. A support layer for the system's Parkinson's

Parkinson's Research: Dopamine, BDNF and Peptides

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Transcript

Parkinson's. 10 million people live with it worldwide. Most
start by dismissing the early
signs. Here's what it feels like. You raise a cup of coffee
and watch your hand shake without
permission. You sign your name and the letters get smaller
as you go. You button your shirt and
your fingers do not move as smoothly as they used to. You
walk down the hallway and your feet stop
landing where you sent them. You turn to look behind you
and your whole body has to follow.
You look in the mirror and your face does not show what you
are feeling inside. Sleep gets shallow.
Mornings get heavy. Words come out softer than you remember
sending them. Here is what is happening
underneath. Deep in the brain, there is a small region that
acts like the volume knob for movement.
Inside it, a specific group of cells make dopamine, the
chemical that lets the brain send smooth signals
to the body. In Parkinson's, those cells slowly stop firing
. The volume knob gets turned down.
Movement signals reach the body weaker. The mitochondria
inside those cells run out of fuel.
And the cells that should protect the neurons get tired.
Two peptides can support this.
Semax is a small protective peptide built for the brain. It
crosses the blood-brain barrier
and tells the surviving cells to stay strong by boosting BD
NF, a growth factor that helps neurons
hold their connections. The cells most affected by
Parkinson's are exactly the ones Semax was designed
to support. NAD+ is the cofactor that powers every cell.
Levels drop with age and drop further when neurons are
under stress. Restoring it gives the surviving cells the
energy to keep firing. When the protective signal
is up and the cellular fuel is back, the system gets help
where it needs it most. The hand can feel steadier.
The morning can feel lighter. Sleep can come back. The face
can soften back into expression. Words can come out clearer
.
Not a cure. A support layer for the system's Parkinson's

Transcript

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Transcript

Watch the film

Listen anywhere